Not surprisingly, the biotech hubs cluster at the top.  Boston leads at $1.9B, New York $1.4B, Seattle, Philadelphia and Baltimore all coming in around $900M each.

Somewhat surprising is how high Boston ranks relative to San Francisco ($680M). Consolidating San Francisco, Stanford, and Berkeley vs. Boston and Cambridge (U.S.) doesn’t change the ranking much.

Boston does have the highest concentration of research universities and hospitals in the country.  By itself, the five-block square Longwood medical area (Harvard Med, Harvard Public Health, Children’s Hospital, Brigham and Women’s, Beth Israel Deaconess, Dana Farber, etc.) totals over $1 billion, which would make it the third highest “city” on the list.

Data source:  U.S.  National Institutes of Health, FY 2016 funding.