New Horizons has communicated with mission control

All systems normal after flying within 7800 miles of Pluto; first images to be released tomorrow afternoon.  New Horizons is about three billion miles away from earth, and it took nine and a half years to get there (even radio signals take about 4 hours).

Saw lots of happy people at mission control tonight on the NASA video feed.

Flight Controllers celebrate after they received confirmation from the spacecraft that it had successfully completed the flyby of Pluto, Tuesday, July 14, 2015 in the Mission Operations Center (MOC) of the Johns Hopkins University Applied Physics Laboratory (APL). Credits: NASA/Bill Ingalls

Here’s what Pluto looked like at a distance of 476,000 miles: 

 

Credit: NASA/Johns Hopkins University Applied Physics Laboratory/Southwest Research Institute

  
More to come tomorrow!

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Pluto, July 11

071215_Pluto_Alone

Pluto as seen from New Horizons on July 11, 2015. Credit: NASA/JHUAPL/SWRI

This image is the last look at Pluto’s Charon-facing hemisphere. with some intriguing hints of features that may be impact craters and ridges.  Unfortunately, there won’t be any higher resolution images collected.  As it passes Pluto on Tuesday, New Horizons will be imaging the opposite side of the planet.

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Rise in cloud computing starts to cut revenue for IT outsourcing companies

Sean McLain, writing in the Wall Street Journal, describes how the shift to cloud computing is dramatically reducing the number of IT support staff needed to maintain and customize servers and software, and the result is a big drop in hiring of outsourced IT staff.  AstraZeneca, a major biopharmaceutical firm, is planning a 50% reduction in its outsourcing budget:

AstraZeneca PLC is sharply scaling back the business it gives to the Indian outsourcing companies that it has long relied on for tech help.

David Smoley, AstraZeneca’s technology chief, said he expects to cut in half the $750 million the drug maker used to spend annually on outsourcing over the next two years. He said the number of people working on information technology also would drop by 50%.

The changes at AstraZeneca are part of a major shift toward cloud computing, which is starting to bite into the revenue and profits as well as hiring in India’s critical outsourcing industry and poses an existential threat to the players that fail to adapt.

Outsourcing executives are bracing for a big disruption.

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Pluto, July 8

2015/07/img_0282.png
(from NASA and JHAPL’s latest update)

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Seven days until New Horizons reaches Pluto

 

Alien base.  That’s my prediction.  Stay tuned.

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Sigh of relief: Cargo mission launches successfully toward ISS

Leading up to yesterday, the two most recent (and three of the last seven) missions to the International Space Station had failed.  Needless to say, concerns were building about the ability to keep the ISS supplied.  Fortunately, Friday’s launch of a Progress cargo capsule went well, and the vehicle is on track for rendezvous with the station on July 5.

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Conjunction of Venus and Jupiter

Venus and Jupiter as seen from the summit of Cadillac Mountain, Bar Harbor ME.  June 29, 2015.

Venus and Jupiter as seen from the summit of Cadillac Mountain, Bar Harbor ME. June 29, 2015.

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SpaceX Falcon 9 Launch Fails

 Today’s launch of a Dragon cargo capsule full of supplies for the International Space Station did not go well.  The Falcon 9 rocket exploded shortly before second stage ignition.  Video clip here.

This was the first Falcon 9 failure after 18 successful launches, but there have been recent Russian launch failures as well. All together, two [correction: three] cargo shipments to the ISS have been lost in the last few months, and experts are starting to get concerned.  Already a planned increase in crew size has been delayed.

Let’s hope the engineering teams can quickly figure out what went wrong and get their programs back on track.

[update] Another ISS cargo shipment is scheduled for launch Friday from Russia; keep your fingers crossed.

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Biopharmaceutical Innovation Hubs and the Future of Work

Innovation hubs such as metro Boston are all the rage.  Urban living is back in style, face-to-face communication trounces teleconferences, and innovation-starved pharma companies are looking to academic centers for new targets and new enabling technologies.  Academic institutions in turn are looking to commercialize anything they can.  In many ways NIH funding is the starter fuel that drives innovation, and it’s advantageous to be located near venture capital firms when you want to launch a promising idea into a new biotech company. Throw in some fringe benefits like easing the two body problem for professional couples, and the attraction of world class cultural institutions, and it’s no wonder the hub band wagon is getting crowded.

There’s another trend developing, too — disaggregation of the biopharma industry.  More and more activities are outsourced and programs are assembled from building blocks of assays and capabilities that exist at a variety of different external partners.  The line between academia and industry is getting blurry.  In the extreme case, virtual companies are springing up.  And it’s a lot easier to source capabilities and use shared facilities within a local innovation hub.

However, not everywhere can be a hub.  Like the tech industry — although there’s a lot of small scale innovation, lots of startups, etc. — there’s also a distinct feeling of consolidation in biopharma.  And perhaps a growing resemblance to a tournament system that may in the end produce relatively fewer winners, with a long tail of those just getting by (companies as well as workers).  Adam Davidson has commented on this trend recently in an article titled “What Hollywood Can Teach Us About the Future of Work” and there are some parallels to biopharma.  While consulting on a Hollywood film, Adam saw an amazing team of successful professionals coming together and expertly making a movie.  Unlike the days of the old large studio system (or in other stable firms of 20th century), in the new world of work teams assemble and disassemble rapidly with few long term relationships between employer and employee.  Workers are exposed constantly to the market for their skills.  Their relative worth is measured all the time, and winners find a lot of exciting and lucrative work.  However, for the average worker, life can be harder than it was in a big stable firm a few decades ago.  You can also hear an interview of David in this podcast.  It’s worth a listen.

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Bristol Meyers Squibb Joins the R&D Hub Consolidation in Cambridge, Massachusetts

BMS has just announced that it will be closing its Wallingford, Connecticut facility and relocating much of R&D to Cambridge MA.  Derek Lowe has some coverage.

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